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- Those who speak of a plaster, generally means the simple wound and fixing plaster to supply the many, small superficial injuries in our daily lives. Here this simple form of the patch is developed only in the past 100 years.
In contrast, the traditional healing plaster applies - Latin Emplastrum - one of the oldest Arzneidarreichungsformen ever. Already by 1000 these patches were applied and used by the ancient Egyptians about the Greeks and Romans in almost all cultures for therapeutic purposes, such as pain BC - and migraine treatments, liver disease, cancer, etc. Up until the middle of the 20th century played the manufacture of medicinal plasters such as lead patch (Emplastrum Lithargyril) at any pharmacy an important role. The matrix consisted mostly of lead salts of higher fatty acids, fats, oils, waxes, resins, turpentine, or mixtures thereof. Since plaster were limited as drug form only a few medical applications such as rheumatic diseases, calluses and skin warts.
Not until the early eighties new indications such as motion sickness (scopolamine), angina pectoris (nitroglycerin), hormone replacement therapy (estradiol) or high blood pressure (clonidine) were developed and commercially disseminated the active substance patches. It has been proven that drugs in therapeutically effective amounts through the skin (transdermal) get into the bloodstream.
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